Potential Roles of Arnt2 in Zebrafish Larval Development
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چکیده
منابع مشابه
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Malformations of the cardiac endocardial cushions (ECs) and valves are common congenital dysmorphisms in newborn infants. Many regulators of EC development have been identified, but the process of valve maturation is less well understood. Zebrafish have been used to understand cardiogenesis through 6 days postfertilization, yet mature heart valves are not present at this stage. By analyzing val...
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ZfAHR2 has been identified as the receptor that is essential for mediating the developmental toxicity caused by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in zebrafish. One form of zfARNT2, zfARNT2b, forms a functional heterodimer with zfAHR2 that specifically recognizes XREs in gel shift experiments and induces XRE-driven transcription in COS-7 cells treated with TCDD. However, it has not been...
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Control of behavior in the natural environment where sensory stimuli are abundant requires superfluous information to be ignored. In part, this is achieved through selective transmission, or gating of signals to motor systems. A quantitative and clinically important measure of sensorimotor gating is prepulse inhibition (PPI) of the startle response, impairments in which have been demonstrated i...
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Mammals fail in sensory and motor recovery following spinal cord injury due to lack of axonal regrowth below the level of injury as well as an inability to reinitiate spinal neurogenesis. However, some anamniotes including the zebrafish Danio rerio exhibit both sensory and functional recovery even after complete transection of the spinal cord. The adult zebrafish is an established model organis...
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ژورنال
عنوان ژورنال: Zebrafish
سال: 2009
ISSN: 1545-8547,1557-8542
DOI: 10.1089/zeb.2008.0536